The Niessing lab mainly uses X-ray crystallography and biochemistry to understand mechanistic principles of RNA-mediated gene regulation in eukaryotes. Besides mRNA localization, a main focus is on translational control. We participate in the FOR2333 Research Unit with two projects:
Project 2: We wish to study neuronal mRNA transport by focussing on the specificity of RNA binding proteins such as Staufen2 and their interplay with co-factors. For this project we collaborate with the Kiebler lab.
Selected publications by the Niessing lab:
- Edelmann et al. Nature Struct Mol Biol (2017) [pubmed]
- Weber et al. eLife 5: 10.7554/eLife.11297 (2016) [pubmed]
- Niedner et al. PNAS 110: E5049-58 (2013) [pubmed]
- Heym et al. J Cell Biol 203: 971-84 (2013) [pubmed]
- Müller et al. PLoS Biol e1000611 (2011) [pubmed]
Dierk Niessing serves as Speaker of the FOR2333.
Helmholtz Zentrum München