Niessing lab

Dierk Niessing

The Niessing lab mainly uses X-ray crystallography and biochemistry to understand mechanistic principles of RNA-mediated gene regulation in eukaryotes. Besides mRNA localization, a main focus is on translational control. We participate in the FOR2333 Research Unit with two projects:

Project 1: Together with the Jansen and Zarnack labs, we use the model system budding yeast to understand what defines a zip-code element and how translational control is achieved on the ASH1 mRNA.

Project 2: We wish to study neuronal mRNA transport by focussing on the specificity of RNA binding proteins such as Staufen2 and their interplay with co-factors. For this project we collaborate with the Kiebler lab.

Selected publications by the Niessing lab:

  • Edelmann et al. Nature Struct Mol Biol (2017) [pubmed]
  • Weber et al. eLife 5: 10.7554/eLife.11297 (2016) [pubmed]
  • Niedner et al. PNAS 110: E5049-58 (2013) [pubmed]
  • Heym et al. J Cell Biol 203: 971-84 (2013) [pubmed]
  • Müller et al. PLoS Biol e1000611 (2011) [pubmed]

Dierk Niessing serves as Speaker of the FOR2333.


Ulm University
Institute of Pharmaceutical Biotechnology
James Franck Ring N27, 89081 Ulm
Website at Uni Ulm


Helmholtz Zentrum München
Niessing lab, Institute of Structural Biology
Ingolstädter Landstr. 1, 85764 Neuherberg
Website at Helmholtz