Category: News

Feldbrügge lab publishes a novel link between long-distance endosomal transport and endocytic traffic

In particular in highly polarized cells like fungal hyphal early endosomes carry out two distinct functions. Firstly, during endocytosis they function as transport unit to deliver cargo towards the lysosome/vacuole. Secondly, the same early endosomes are used to deliver cargo like

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Methods workshop held at EMBL in March 2017

From March 13.-15. 2017 the FOR2333 team held a three-days methods workshop at the Advanced Training Centre of the EMBL Heidelberg. Students of participating groups attended training sessions on “bioinformatics”, “professional preparation of scientific figures”, “introduction to structural biology”, and

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Ephrussi lab publishes an unconventional mechanism that loads the kinesin-1 motor onto oskar mRNPs

In this study, the Ephrussi lab shows that an atypical tropomyosin isoform is a direct (m)RNA binding protein that binds preferentially to the dimerizing oskar 3’ UTR and is a component of the transported oskar mRNPs within the female germ-line.

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Zarnack publishes a meta-analysis of CLIP data in Genome Biology

In collaboration with Jernej Ule’s group at the Francis Crick Institute in London, UK, the Zarnack lab explores how different experimental steps can constrain the identification of RBP binding sites in CLIP experiments. To this end, they analysed publicly available

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Niessing lab publishes structures of ASH1 mRNP in Nature Struct. Mol. Biol.

In this study the Niessing lab solved three X-ray structures to understand how the E3 localization element of the ASH1 mRNA is folded, how it is recognized in the nucleus by She2p, and how highly specific binding in the cytoplasmic is achieved

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Helena Jambor now fellow at “Wissenschaftskolleg zu Berlin”

Dr. Helena Jambor (mentee of the DFG-research unit) has recently been accepted as fellow at the Institute for Advanced Studies (Wissenschaftskolleg zu Berlin), were she researches the history of life science visualization. (

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Second FOR2333 meeting from September 5.-7. 2016 in Düsseldorf

Our research network met again, this time at the “Haus der Universität” in Düsseldorf. The focus of this meeting was to foster collaborations and initiate new projects. As local guest speaker we had Prof. Heiner Schaal (Institute of Virology, HHUD)

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Congratulations! Bono and Ephrussi labs publish in Nature Struc Mol Biol and Nature Comm.

The group of Fulvia Bono published a structure-to-functional analysis of the bicoid mRNA-localization factor Exuperantia (Exu) from Drosophila. Their crystal structure shows that Exu forms a dimer and that each subunit consists of a catalytically inactive 3’-5’ EXO domain and

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First FOR2333 meeting on March 1.- 2. in Blaubeuren

Our first meeting of the DFG Research Unit 2333 (FOR2333) took place on March 1st and 2nd in the guesthouse of the University Tübingen in Blaubeuren. We enjoyed our first get-together with excellent discussions and talks. Looking forward to our

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DFG decision: FOR2333 Research Unit will be funded!

Our DFG Research Unit 2333 on „mRNA localization“ just received a positive funding decision from the DFG. We are excited and look forward to start our network. More details will follow soon…  (October 15th 2015) Press releases: Tuebingen University / Duesseldorf

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