Author: Dierk_Niessing

FOR2333 meeting from September 25th to 27th at the MPI for Developmental Biology in Tübingen

This time our regular network meeting took place in the cozy town of Tübingen in the middle of Baden-Württemberg. It was a wonderful get-together and a great opportunity to discuss the latest scientific results in RNA localization. Thanks to Ralf-Peter

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FOR2333 members participate in EMBO “RNA localization” conference in Italy

Lab members of the FOR2333 network participated in the EMBO conference “RNA localisation and local translation” in Barga, Italy. The conference took place from July 23rd to 28th 2017 at the beautiful Il Ciocco Resort in Tuscany and was packed

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Feldbrügge lab publishes a novel link between long-distance endosomal transport and endocytic traffic

In particular in highly polarized cells like fungal hyphal early endosomes carry out two distinct functions. Firstly, during endocytosis they function as transport unit to deliver cargo towards the lysosome/vacuole. Secondly, the same early endosomes are used to deliver cargo like

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Methods workshop held at EMBL in March 2017

From March 13.-15. 2017 the FOR2333 team held a three-days methods workshop at the Advanced Training Centre of the EMBL Heidelberg. Students of participating groups attended training sessions on “bioinformatics”, “professional preparation of scientific figures”, “introduction to structural biology”, and

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Ephrussi lab publishes an unconventional mechanism that loads the kinesin-1 motor onto oskar mRNPs

In this study, the Ephrussi lab shows that an atypical tropomyosin isoform is a direct (m)RNA binding protein that binds preferentially to the dimerizing oskar 3’ UTR and is a component of the transported oskar mRNPs within the female germ-line.

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Zarnack publishes a meta-analysis of CLIP data in Genome Biology

In collaboration with Jernej Ule’s group at the Francis Crick Institute in London, UK, the Zarnack lab explores how different experimental steps can constrain the identification of RBP binding sites in CLIP experiments. To this end, they analysed publicly available

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Niessing lab publishes structures of ASH1 mRNP in Nature Struct. Mol. Biol.

In this study the Niessing lab solved three X-ray structures to understand how the E3 localization element of the ASH1 mRNA is folded, how it is recognized in the nucleus by She2p, and how highly specific binding in the cytoplasmic is achieved

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Helena Jambor now fellow at “Wissenschaftskolleg zu Berlin”

Dr. Helena Jambor (mentee of the DFG-research unit) has recently been accepted as fellow at the Institute for Advanced Studies (Wissenschaftskolleg zu Berlin), were she researches the history of life science visualization. (https://www.youtube.com/watch?v=df2sX4JTscw&feature=youtu.be).

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Second FOR2333 meeting from September 5.-7. 2016 in Düsseldorf

Our research network met again, this time at the “Haus der Universität” in Düsseldorf. The focus of this meeting was to foster collaborations and initiate new projects. As local guest speaker we had Prof. Heiner Schaal (Institute of Virology, HHUD)

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Congratulations! Bono and Ephrussi labs publish in Nature Struc Mol Biol and Nature Comm.

The group of Fulvia Bono published a structure-to-functional analysis of the bicoid mRNA-localization factor Exuperantia (Exu) from Drosophila. Their crystal structure shows that Exu forms a dimer and that each subunit consists of a catalytically inactive 3’-5’ EXO domain and

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